Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 11/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24668653 | 0.84 | CA2 (0.50) | CA2 | |
| SCHEMBL24670395 | 0.67 | CA2 (0.42) | CA2PDPK1 | |
| SCHEMBL21586454 | 0.65 | CA2 (0.58) | CA2 | |
| SCHEMBL12671956 | 0.63 | TDP1 (0.35) | — | |
| SCHEMBL24668657 | 0.63 | LOX (0.34) | CA2PDPK1SMN1; SMN2 | |
| SCHEMBL24669733 | 0.62 | PDPK1 (0.31) | PDPK1 | |
| SCHEMBL7139485 | 0.62 | CA2 (0.42) | CA2 | |
| SCHEMBL30067654 | 0.60 | CA2 (0.54) | CA2SMN1; SMN2 | |
| SCHEMBL24743674 | 0.60 | CA2 (0.45) | CA2 | |
| SCHEMBL14466905 | 0.60 | PTGS2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022187693-A1 | COVALENT CDK2-BINDING COMPOUNDS FOR THERAPEUTIC PURPOSES | UMBRA THERAPEUTICS INC. (US) | 2022-09-09 | — | — | WO | disclosed |