Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 6/20 | 0.61 |
| ▸ | WNT3A | P56704 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.45 |
| ▸ | KIT | P10721 | 1/20 | 0.45 |
| ▸ | CDK7 | P50613 | 1/20 | 0.45 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.45 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.45 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.43 |
| ▸ | GRM5 | P41594 | 2/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24671229 | 0.91 | NAMPT (0.51) | NAMPTWNT3AGPR119KITGRM1 | |
| SCHEMBL29803758 | 0.88 | NAMPT (0.48) | NAMPTWNT3AGPR119KITGRM1 | |
| SCHEMBL24670472 | 0.86 | NAMPT (0.49) | NAMPTWNT3AGPR119KITGRM1 | |
| SCHEMBL24670478 | 0.84 | NAMPT (0.47) | NAMPT | |
| SCHEMBL29803797 | 0.84 | NAMPT (0.47) | NAMPT | |
| SCHEMBL24669280 | 0.83 | NAMPT (0.62) | NAMPTWNT3AKITCDK7CDK13 | |
| SCHEMBL24669916 | 0.83 | NAMPT (0.59) | NAMPTWNT3AKITCDK7CDK13 | |
| SCHEMBL31705452 | 0.83 | GPR119 (0.48) | NAMPTGPR119GRM1GRM5CYP11B2 | |
| SCHEMBL31705574 | 0.83 | GPR119 (0.48) | NAMPTGPR119GRM1GRM5CYP11B2 | |
| SCHEMBL24669223 | 0.82 | NAMPT (0.61) | NAMPTWNT3AGPR119KITCDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |