Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | WNT3A | P56704 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.40 |
| ▸ | GRM5 | P41594 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | EED | O75530 | 2/20 | 0.38 |
| ▸ | RBBP4 | Q09028 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29803758 | 0.92 | NAMPT (0.48) | NAMPTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL24671229 | 0.88 | NAMPT (0.51) | NAMPTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL24669181 | 0.86 | NAMPT (0.61) | NAMPTWNT3AGPR119KITGRM1 | |
| SCHEMBL24671267 | 0.84 | NAMPT (0.49) | NAMPTWNT3AGPR119KITGRM1 | |
| SCHEMBL29803354 | 0.84 | HDAC3 (0.41) | NAMPTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL24669882 | 0.84 | HDAC3 (0.41) | NAMPTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29803379 | 0.83 | NAMPT (0.55) | NAMPTWNT3AKITDRD2SCN9A | |
| SCHEMBL24670460 | 0.82 | NAMPT (0.49) | NAMPTWNT3AKITGRM1GRM5 | |
| SCHEMBL24891933 | 0.80 | NAMPT (0.55) | NAMPTWNT3AKITGRM1GRM5 | |
| SCHEMBL24892373 | 0.80 | NAMPT (0.55) | NAMPTWNT3AKITGRM1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |