Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | WNT3A | P56704 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.45 |
| ▸ | GRM1 | Q13255 | 4/20 | 0.43 |
| ▸ | GRM5 | P41594 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | EED | O75530 | 2/20 | 0.41 |
| ▸ | RBBP4 | Q09028 | 2/20 | 0.41 |
| ▸ | SUZ12 | Q15022 | 2/20 | 0.41 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24669181 | 0.91 | NAMPT (0.61) | NAMPTWNT3AGPR119GRM1GRM5 | |
| SCHEMBL29803758 | 0.90 | NAMPT (0.48) | NAMPTWNT3AGPR119GRM1GRM5 | |
| SCHEMBL24670472 | 0.88 | NAMPT (0.49) | NAMPTWNT3AGPR119GRM1GRM5 | |
| SCHEMBL31705574 | 0.82 | GPR119 (0.48) | NAMPTGPR119GRM1GRM5PDK4 | |
| SCHEMBL31705452 | 0.82 | GPR119 (0.48) | NAMPTGPR119GRM1GRM5PDK4 | |
| SCHEMBL24669894 | 0.78 | HDAC3 (0.40) | NAMPTWNT3AMAPTKITHDAC3 | |
| SCHEMBL29803417 | 0.78 | HDAC3 (0.40) | NAMPTWNT3AMAPTKITHDAC3 | |
| SCHEMBL24670464 | 0.78 | HDAC3 (0.40) | NAMPTWNT3AMAPTKITHDAC3 | |
| SCHEMBL29803354 | 0.77 | HDAC3 (0.41) | NAMPTWNT3AHDAC3HDAC4HDAC1 | |
| SCHEMBL23164675 | 0.77 | NAMPT (0.49) | NAMPTWNT3AGPR119GRM1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |