Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL29803859 | 0.94 | ALDH1A1 (0.36) | MAPTSMN1; SMN2MAPKAPK2MAPK1HSD17B10 | |
| SCHEMBL24671486 | 0.90 | MAPT (0.38) | MAPTSMN1; SMN2MAPKAPK2MAPK1HSD17B10 | |
| SCHEMBL24670895 | 0.85 | TMPRSS2 (0.44) | MAPTSMN1; SMN2TSHRALDH1A1KMT2A | |
| SCHEMBL24891809 | 0.81 | NPC1 (0.40) | MAPTSMN1; SMN2TSHRALDH1A1HPGD | |
| SCHEMBL24891892 | 0.81 | NPC1 (0.40) | MAPTSMN1; SMN2TSHRALDH1A1HPGD | |
| SCHEMBL24671076 | 0.80 | PTPN11 (0.38) | TMPRSS2NAMPT | |
| SCHEMBL24671165 | 0.80 | ALDH1A1 (0.36) | MAPTSMN1; SMN2TSHRALDH1A1KMT2A | |
| SCHEMBL24671385 | 0.79 | MCHR1 (0.42) | MAPTSMN1; SMN2TSHRALDH1A1HPGD | |
| SCHEMBL24668998 | 0.79 | TMPRSS2 (0.42) | KMT2AMEN1TMPRSS2ST14NAMPT | |
| SCHEMBL29803078 | 0.79 | TMPRSS2 (0.42) | KMT2AMEN1TMPRSS2ST14NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | claimed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |