Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 3/20 | 0.43 |
| ▸ | NOS1 | P29475 | 2/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.41 |
| ▸ | KIF11 | P52732 | 5/20 | 0.40 |
| ▸ | ARG1 | P05089 | 1/20 | 0.40 |
| ▸ | ARG2 | P78540 | 1/20 | 0.40 |
| ▸ | BHMT | Q93088 | 2/20 | 0.39 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24374520 | 0.87 | SLC7A5 (0.48) | SLC7A5NOS2NOS1NOS3SLC1A3 | |
| SCHEMBL24359839 | 0.87 | SLC7A5 (0.48) | SLC7A5NOS2NOS1NOS3SLC1A3 | |
| Cystine SCHEMBL28213243 | 0.85 | SLC7A5 (0.50) | SLC7A5NOS2NOS1NOS3SLC1A3 | |
| Cystine SCHEMBL127805 | 0.84 | PTGS1 (0.50) | SLC7A5NOS2NOS1NOS3SLC1A3 | |
| Cystine SCHEMBL222059 | 0.84 | PTGS1 (0.50) | SLC7A5NOS2NOS1NOS3SLC1A3 | |
| Cystine SCHEMBL8332356 | 0.84 | PTGS1 (0.50) | SLC7A5NOS2NOS1NOS3SLC1A3 | |
| Cystine SCHEMBL10224 | 0.84 | PTGS1 (0.50) | SLC7A5NOS2NOS1NOS3SLC1A3 | |
| Cystine SCHEMBL5018669 | 0.84 | PTGS1 (0.50) | SLC7A5NOS2NOS1NOS3SLC1A3 | |
| Cystine SCHEMBL21114356 | 0.84 | PTGS1 (0.50) | SLC7A5NOS2NOS1NOS3SLC1A3 | |
| Cystine SCHEMBL8332360 | 0.84 | PTGS1 (0.50) | SLC7A5NOS2NOS1NOS3SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220332749-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS | Azura Ophthalmics Ltd. (IL) | 2022-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220332749-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS | MPO, MUC1, CRYAB | SLC7A5 3994/4885NOS2 2024/4885NOS1 1880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.