Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24669715 | 0.77 | — | — | |
| SCHEMBL24669724 | 0.70 | CA2 (0.38) | CA2CA12CA1CA9CA14 | |
| SCHEMBL24516781 | 0.67 | ALDH1A1 (0.51) | — | |
| SCHEMBL617257 | 0.66 | ALOX5AP (0.35) | — | |
| SCHEMBL16347825 | 0.65 | ALOX5 (0.32) | — | |
| SCHEMBL31607907 | 0.65 | CYP1A2 (0.38) | — | |
| SCHEMBL2168948 | 0.64 | — | — | |
| SCHEMBL20764825 | 0.64 | FFAR1 (0.33) | — | |
| SCHEMBL18369541 | 0.62 | — | — | |
| SCHEMBL8526099 | 0.62 | CYP1A2 (0.41) | CA2CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022187693-A1 | COVALENT CDK2-BINDING COMPOUNDS FOR THERAPEUTIC PURPOSES | UMBRA THERAPEUTICS INC. (US) | 2022-09-09 | — | — | WO | disclosed |