Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.50 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.48 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP27B1 | O15528 | 2/20 | 0.45 |
| ▸ | CYP24A1 | Q07973 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2468306 | 0.88 | GPR139 (0.51) | GPR139SLC6A9SLC6A5KDM4EGAA | |
| SCHEMBL2465220 | 0.88 | SLC6A9 (0.54) | SLC6A9SLC6A5GAACYP24A1RAB9A | |
| SCHEMBL2467017 | 0.85 | GPR139 (0.55) | GPR139SLC6A9SLC6A5KDM4EGAA | |
| SCHEMBL14243641 | 0.84 | SLC6A9 (0.51) | GPR139SLC6A9SLC6A5KDM4EGAA | |
| SCHEMBL2470778 | 0.83 | GPR139 (0.53) | GPR139SLC6A9SLC6A5KDM4EGAA | |
| SCHEMBL2466319 | 0.82 | GPR139 (0.49) | GPR139SLC6A9SLC6A5KDM4EGAA | |
| SCHEMBL2463921 | 0.80 | HTT (0.47) | GPR139RAB9ASMN1; SMN2NPC1HTT | |
| SCHEMBL2467722 | 0.79 | HTT (0.46) | RAB9ASMN1; SMN2NPC1HTTTP53 | |
| SCHEMBL2466996 | 0.79 | GPR139 (0.51) | GPR139SLC6A9SLC6A5KDM4EGAA | |
| SCHEMBL2462153 | 0.78 | HPGD (0.47) | GPR139KDM4ERAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2539378-B1 | HALOGENATED AMIDE ESTER AND INTERNAL ELECTRON DONOR WITH SAME | GRACE W R & CO (US) | 2018-06-06 | — | — | EP | disclosed |
| US-8466081-B2 | Halogenated amide ester and internal electron donor with same | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-06-18 | — | — | US | disclosed |
| EP-2539378-A1 | HALOGENATED AMIDE ESTER AND INTERNAL ELECTRON DONOR WITH SAME | Dow Global Technologies LLC (US) | 2013-01-02 | — | — | EP | disclosed |
| US-20120322964-A1 | Halogenated Amide Ester and Internal Electron Donor with Same | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-12-20 | — | — | US | disclosed |
| WO-2011106497-A1 | HALOGENATED AMIDE ESTER AND INTERNAL ELECTRON DONOR WITH SAME | DOW GLOBAL TECHNOLOGIES LLC (US) | 2011-09-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120322964-A1 | Halogenated Amide Ester and Internal Electron Donor with Same | NAT10, NAT1, NAA50 | GPR139 3497/4885SLC6A9 963/4885SLC6A5 763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.