Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.52 |
| ▸ | UBE2N | P61088 | 1/20 | 0.52 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4070219 | 0.85 | HPSE (0.48) | RAD52UBE2NHPSEMAPTALDH1A1 | |
| SCHEMBL3597291 | 0.82 | ABL1 (0.55) | HPSEMAPTALDH1A1APEX1KDM4E | |
| SCHEMBL28521765 | 0.79 | HSP90AA1 (0.60) | HPSEMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL24670060 | 0.79 | RAD52 (0.59) | RAD52UBE2NMAPTALDH1A1KDM4E | |
| SCHEMBL7348242 | 0.76 | MAPT (0.68) | RAD52MAPTALDH1A1APEX1KDM4E | |
| SCHEMBL7468736 | 0.75 | HPSE (0.62) | HPSEMAPTALDH1A1KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL7231030 | 0.74 | HPSE (0.61) | HPSEMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL4070212 | 0.73 | KDM4E (0.51) | MAPTALDH1A1APEX1KDM4EMEN1 | |
| SCHEMBL24670085 | 0.73 | RAD52 (0.63) | RAD52UBE2NMAPTALDH1A1APEX1 | |
| SCHEMBL38661086 | 0.73 | IDO1 (0.59) | MAPTALDH1A1APEX1NPSR1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022187693-A1 | COVALENT CDK2-BINDING COMPOUNDS FOR THERAPEUTIC PURPOSES | UMBRA THERAPEUTICS INC. (US) | 2022-09-09 | — | — | WO | disclosed |