Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 19/20 | 0.74 |
| ▸ | CA1 | P00915 | 18/20 | 0.74 |
| ▸ | CA12 | O43570 | 13/20 | 0.58 |
| ▸ | CA9 | Q16790 | 13/20 | 0.58 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30849522 | 0.83 | CA1 (0.52) | CA2CA1CA12CA9 | |
| SCHEMBL25738457 | 0.83 | CA1 (0.88) | CA2CA1CA12CA9 | |
| SCHEMBL16024065 | 0.82 | MAPT (0.51) | CA2CA1 | |
| SCHEMBL16024081 | 0.81 | CA1 (0.49) | CA2CA1CA12CA9 | |
| SCHEMBL17471214 | 0.81 | CA1 (0.49) | CA2CA1CA12CA9 | |
| SCHEMBL10126690 | 0.81 | MTNR1A (0.60) | CA2CA1 | |
| SCHEMBL2991645 | 0.81 | MAPK1 (0.53) | CA2CA1 | |
| SCHEMBL26647873 | 0.80 | CA2 (0.56) | CA2CA1CA12CA9 | |
| SCHEMBL23099820 | 0.80 | CA1 (0.76) | CA2CA1CA12CA9STAT3 | |
| SCHEMBL1186595 | 0.80 | CA1 (0.69) | CA2CA1CA12CA9STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022187693-A1 | COVALENT CDK2-BINDING COMPOUNDS FOR THERAPEUTIC PURPOSES | UMBRA THERAPEUTICS INC. (US) | 2022-09-09 | — | — | WO | disclosed |