Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 16/20 | 0.88 |
| ▸ | CA2 | P00918 | 16/20 | 0.88 |
| ▸ | CA12 | O43570 | 6/20 | 0.56 |
| ▸ | CA9 | Q16790 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23099820 | 0.88 | CA1 (0.76) | CA1CA2CA12CA9KMT2A | |
| SCHEMBL1186595 | 0.84 | CA1 (0.69) | CA1CA2CA12CA9 | |
| SCHEMBL15584781 | 0.83 | CA1 (0.62) | CA1CA2PKMALDH1A1 | |
| SCHEMBL24670062 | 0.83 | CA2 (0.74) | CA1CA2CA12CA9 | |
| SCHEMBL14679432 | 0.82 | CA1 (0.60) | CA1CA2KMT2AMEN1ALDH1A1 | |
| SCHEMBL13233243 | 0.82 | CA1 (0.60) | CA1CA2ALDH1A1 | |
| SCHEMBL16747675 | 0.81 | GAA (0.61) | CA1CA2KMT2AMEN1ALDH1A1 | |
| SCHEMBL4752807 | 0.81 | CA1 (0.59) | CA1CA2KMT2AMEN1ALDH1A1 | |
| SCHEMBL4758303 | 0.81 | CA1 (0.59) | CA1CA2KMT2APKMALDH1A1 | |
| SCHEMBL6274441 | 0.80 | CA1 (0.58) | CA1CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023102140-A1 | TMPRSS2 INHIBITORS AND METHODS OF USE | TOPSPIN THERAPEUTICS, INC. (US) | 2023-06-08 | — | — | WO | disclosed |