Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 8/20 | 0.59 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.43 |
| ▸ | NAMPT | P43490 | 3/20 | 0.42 |
| ▸ | PLAU | P00749 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29802975 | 1.00 | TMPRSS2 (0.59) | TMPRSS2ITGB3ITGA2BNAMPTPLAU | |
| SCHEMBL24669348 | 0.95 | TMPRSS2 (0.61) | TMPRSS2ITGB3ITGA2BNAMPTPLAU | |
| SCHEMBL29803057 | 0.95 | TMPRSS2 (0.61) | TMPRSS2ITGB3ITGA2BNAMPTPLAU | |
| SCHEMBL29803214 | 0.92 | TMPRSS2 (0.52) | TMPRSS2ITGB3ITGA2BNAMPTPLAU | |
| SCHEMBL24669447 | 0.88 | TMPRSS2 (0.48) | TMPRSS2NAMPTNPC1 | |
| SCHEMBL24669458 | 0.88 | TMPRSS2 (0.48) | TMPRSS2ITGB3ITGA2BNAMPTPLAU | |
| SCHEMBL29802861 | 0.88 | TMPRSS2 (0.52) | TMPRSS2NPC1 | |
| SCHEMBL24670643 | 0.88 | TMPRSS2 (0.52) | TMPRSS2NPC1 | |
| SCHEMBL24671270 | 0.88 | TMPRSS2 (0.52) | TMPRSS2ITGB3ITGA2BNAMPTPLAU | |
| SCHEMBL29803204 | 0.88 | TMPRSS2 (0.52) | TMPRSS2ITGB3ITGA2BNAMPTPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |