Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29802861 | 1.00 | TMPRSS2 (0.52) | TMPRSS2MAPTLMNAMEN1KMT2A | |
| SCHEMBL29803214 | 0.93 | TMPRSS2 (0.52) | TMPRSS2MAPTLMNATRPV1NPC1 | |
| SCHEMBL29802931 | 0.93 | TMPRSS2 (0.59) | TMPRSS2MAPTLMNAMEN1KMT2A | |
| SCHEMBL24670920 | 0.91 | CHRM1 (0.53) | TMPRSS2MAPTLMNAMEN1KMT2A | |
| SCHEMBL24669447 | 0.89 | TMPRSS2 (0.48) | TMPRSS2MAPTLMNAHTTALDH1A1 | |
| SCHEMBL24671270 | 0.89 | TMPRSS2 (0.52) | TMPRSS2MAPTLMNAMEN1KMT2A | |
| SCHEMBL29803204 | 0.89 | TMPRSS2 (0.52) | TMPRSS2MAPTLMNAMEN1KMT2A | |
| SCHEMBL29802975 | 0.88 | TMPRSS2 (0.59) | TMPRSS2NPC1 | |
| SCHEMBL24670135 | 0.88 | TMPRSS2 (0.59) | TMPRSS2NPC1 | |
| SCHEMBL24671177 | 0.87 | TMPRSS2 (0.51) | TMPRSS2MAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |