Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 8/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | PLAU | P00749 | 3/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29803057 | 1.00 | TMPRSS2 (0.61) | TMPRSS2NPC1PLAUITGB3ITGA2B | |
| SCHEMBL24670135 | 0.95 | TMPRSS2 (0.59) | TMPRSS2NPC1PLAUITGB3ITGA2B | |
| SCHEMBL29802975 | 0.95 | TMPRSS2 (0.59) | TMPRSS2NPC1PLAUITGB3ITGA2B | |
| SCHEMBL29803214 | 0.91 | TMPRSS2 (0.52) | TMPRSS2NPC1PLAUITGB3ITGA2B | |
| SCHEMBL29803335 | 0.88 | TMPRSS2 (0.69) | TMPRSS2NPC1PLAUITGB3ITGA2B | |
| SCHEMBL24669403 | 0.88 | TMPRSS2 (0.69) | TMPRSS2NPC1PLAUITGB3ITGA2B | |
| SCHEMBL24669447 | 0.88 | TMPRSS2 (0.48) | TMPRSS2NPC1RAB9ASMN1; SMN2NAMPT | |
| SCHEMBL29802849 | 0.87 | TMPRSS2 (0.63) | TMPRSS2NPC1PLAUITGB3ITGA2B | |
| SCHEMBL24671270 | 0.87 | TMPRSS2 (0.52) | TMPRSS2NPC1PLAUITGB3ITGA2B | |
| SCHEMBL24670643 | 0.87 | TMPRSS2 (0.52) | TMPRSS2NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |