Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 3/20 | 0.61 |
| ▸ | HTR2C | P28335 | 6/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.56 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.44 |
| ▸ | CDK9 | P50750 | 1/20 | 0.44 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.43 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4746022 | 0.84 | QDPR (0.62) | QDPRHTR2CSIGMAR1NAMPTP2RY14 | |
| SCHEMBL5603681 | 0.83 | QDPR (0.61) | QDPRHTR2CSIGMAR1NAMPTP2RY14 | |
| SCHEMBL8315937 | 0.82 | CCNT1 (0.61) | QDPRHTR2CSIGMAR1NAMPTSMN1; SMN2 | |
| SCHEMBL18715828 | 0.82 | QDPR (0.56) | QDPRHTR2CSIGMAR1NAMPTCCNT1 | |
| SCHEMBL18121781 | 0.80 | QDPR (0.57) | QDPRHTR2CSIGMAR1NAMPTCCNT1 | |
| SCHEMBL21450621 | 0.79 | QDPR (0.56) | QDPRHTR2CSIGMAR1NAMPTMAPKAPK2 | |
| SCHEMBL24670222 | 0.79 | QDPR (0.56) | QDPRHTR2CSIGMAR1NAMPTMAPT | |
| SCHEMBL13944380 | 0.79 | QDPR (0.51) | QDPRHTR2CSIGMAR1MAPTSMN1; SMN2 | |
| SCHEMBL24670579 | 0.79 | QDPR (0.51) | QDPRHTR2CSIGMAR1NAMPTHSD17B1 | |
| SCHEMBL24670573 | 0.78 | MAPKAPK2 (0.59) | QDPRHTR2CSIGMAR1NAMPTCCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |