Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 3/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.61 |
| ▸ | HTR2C | P28335 | 6/20 | 0.59 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.52 |
| ▸ | GABRP | O00591 | 1/20 | 0.52 |
| ▸ | GABRD | O14764 | 1/20 | 0.52 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.52 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.52 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.52 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.52 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.52 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.52 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.52 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.52 |
| ▸ | GABRE | P78334 | 1/20 | 0.52 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.52 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5603681 | 0.84 | QDPR (0.61) | QDPRSIGMAR1HTR2CP2RY14GABRP | |
| SCHEMBL24670263 | 0.84 | QDPR (0.61) | QDPRSIGMAR1HTR2CP2RY14NAMPT | |
| SCHEMBL18715828 | 0.80 | QDPR (0.56) | QDPRSIGMAR1HTR2CNAMPTMAPKAPK2 | |
| SCHEMBL24670222 | 0.80 | QDPR (0.56) | QDPRSIGMAR1HTR2CP2RY14LMNA | |
| SCHEMBL24670573 | 0.79 | MAPKAPK2 (0.59) | QDPRSIGMAR1HTR2CNAMPTMAPKAPK2 | |
| SCHEMBL29522119 | 0.79 | SIGMAR1 (0.49) | QDPRSIGMAR1HTR2CP2RY14GABRP | |
| Trifluoroacetic Acid SCHEMBL29749858 | 0.79 | QDPR (0.50) | QDPRSIGMAR1HTR2CP2RY14GABRP | |
| SCHEMBL171560 | 0.78 | P4HA1 (0.54) | QDPRSIGMAR1HTR2CP2RY14GABRP | |
| SCHEMBL30080863 | 0.78 | QDPR (0.53) | QDPRSIGMAR1HTR2CP2RY14GABRP | |
| SCHEMBL18121781 | 0.78 | QDPR (0.57) | QDPRSIGMAR1HTR2CP2RY14GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |