Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26005420 | 0.81 | ST14 (0.46) | ST14GAAIDO1LMNAKMT2A | |
| SCHEMBL12997107 | 0.80 | F10 (0.49) | ST14GAAIDO1LMNAPOLB | |
| SCHEMBL20077692 | 0.80 | CA12 (0.49) | ST14GAAIDO1LMNAPOLB | |
| SCHEMBL27115810 | 0.79 | F7 (0.38) | LMNAKMT2AMAPTTDP1ALDH1A1 | |
| SCHEMBL23135379 | 0.79 | ADRA2A (0.45) | ST14GAAIDO1LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL28482528 | 0.79 | F10 (0.48) | ST14IDO1LMNAPOLBKMT2A | |
| SCHEMBL10310202 | 0.78 | NPC1 (0.51) | ST14IDO1LMNAPOLBKMT2A | |
| SCHEMBL10310256 | 0.78 | ST14 (0.49) | ST14IDO1LMNAKMT2AALDH1A1 | |
| SCHEMBL18401402 | 0.78 | ST14 (0.49) | ST14IDO1ALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL12401907 | 0.77 | ST14 (0.51) | ST14GAAIDO1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |