Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20000816 | 0.83 | CA12 (0.49) | CA12CA1CA2CA4CA9 | |
| SCHEMBL12997107 | 0.83 | F10 (0.49) | ST14EPHX1IDO1KMT2ALMNA | |
| SCHEMBL20077884 | 0.82 | EPHX1 (0.47) | EPHX1ALOX5LMNACXCR1CXCR2 | |
| Hydrochloric Acid SCHEMBL28482528 | 0.81 | F10 (0.48) | ST14EPHX1IDO1KMT2ALMNA | |
| SCHEMBL10310256 | 0.80 | ST14 (0.49) | CA1CA2ST14IDO1KMT2A | |
| SCHEMBL18401402 | 0.80 | ST14 (0.49) | CA1CA2ST14IDO1 | |
| SCHEMBL10310202 | 0.80 | NPC1 (0.51) | CA12CA1CA2CA9ST14 | |
| SCHEMBL14012684 | 0.80 | ST14 (0.49) | CA12CA1CA2CA9ST14 | |
| SCHEMBL24670456 | 0.80 | ST14 (0.43) | CA1CA2CA9ST14EPHX1 | |
| SCHEMBL12401907 | 0.80 | ST14 (0.51) | CA1CA2ST14IDO1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10344002-B2 | Compositions and methods for treating metabolic disorders | NUSIRT SCIENCES, INC. (US) | 2019-07-09 | — | — | US | disclosed |
| US-20180105498-A1 | COMPOSITIONS AND METHODS FOR TREATING METABOLIC DISORDERS | NUSIRT SCIENCES, INC. | 2018-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10344002-B2 | Compositions and methods for treating metabolic disorders | LIPC, PC, PNLIP | CA12 1766/4885CA1 2396/4885CA2 1375/4885 |
| US-20180105498-A1 | COMPOSITIONS AND METHODS FOR TREATING METABOLIC DISORDERS | LIPC, PC, PNLIP | CA12 1766/4885CA1 2396/4885CA2 1375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.