Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | MAPKAPK2 | P49137 | 8/20 | 0.49 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24670573 | 0.88 | MAPKAPK2 (0.59) | NAMPTMAPKAPK2 | |
| SCHEMBL24891825 | 0.85 | RAB9A (0.64) | NPC1RAB9AKMT2ASMN1; SMN2MAPT | |
| SCHEMBL8769785 | 0.84 | RAB9A (0.59) | NPC1RAB9AKMT2ASMN1; SMN2MAPT | |
| SCHEMBL24669493 | 0.83 | HTR2A (0.43) | NAMPTKMT2AMEN1HTT | |
| SCHEMBL29803509 | 0.83 | HTR2A (0.43) | NAMPTKMT2AMEN1HTT | |
| SCHEMBL29803377 | 0.83 | NPC1 (0.46) | NAMPTMAPKAPK2NPC1RAB9AKMT2A | |
| SCHEMBL24669213 | 0.83 | MAPKAPK2 (0.49) | NAMPTMAPKAPK2IRAK4NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL29803793 | 0.82 | HTR2A (0.43) | KMT2AMEN1HTTITGB3ITGA2B | |
| SCHEMBL1663115 | 0.81 | ALDH1A1 (0.66) | NPC1RAB9AKMT2ASMN1; SMN2MAPT | |
| SCHEMBL24670840 | 0.80 | MAPT (0.48) | KMT2ASMN1; SMN2MAPTMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |