Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24670304 | 0.87 | NAMPT (0.51) | MAPTTP53THRBSMN1; SMN2NPY2R | |
| SCHEMBL24670840 | 0.87 | MAPT (0.48) | MAPTTP53THRBSMN1; SMN2CYP2C9 | |
| SCHEMBL24670298 | 0.82 | MAPT (0.53) | MAPTTP53THRBSMN1; SMN2NPY2R | |
| SCHEMBL24671575 | 0.81 | MAPT (0.42) | MAPTTP53THRBSMN1; SMN2NPY2R | |
| SCHEMBL24671017 | 0.81 | L3MBTL1 (0.42) | MAPTTP53SMN1; SMN2NPY2R | |
| SCHEMBL24671543 | 0.80 | NAMPT (0.52) | — | |
| SCHEMBL24669379 | 0.80 | NR1H2 (0.49) | — | |
| SCHEMBL24669994 | 0.76 | NAMPT (0.54) | MAPTSMN1; SMN2NPY2R | |
| Trifluoroacetic Acid SCHEMBL29803769 | 0.75 | SLC2A1 (0.44) | MAPT | |
| SCHEMBL29803377 | 0.75 | NPC1 (0.46) | MAPTTP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |