Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | F13A1 | P00488 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | TGM1 | P22735 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24669557 | 0.88 | NAMPT (0.51) | MAPTTP53KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL29803673 | 0.88 | NAMPT (0.51) | MAPTTP53KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL24671574 | 0.86 | MAPKAPK2 (0.52) | MAPTKMT2ASMN1; SMN2MAPK1HTT | |
| SCHEMBL29803320 | 0.86 | MAPKAPK2 (0.52) | MAPTKMT2ASMN1; SMN2MAPK1HTT | |
| SCHEMBL24671017 | 0.84 | L3MBTL1 (0.42) | MAPTTP53KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL24670862 | 0.81 | MAPT (0.46) | MAPTTP53SMN1; SMN2THRBNPY2R | |
| SCHEMBL29803281 | 0.81 | NAMPT (0.49) | MAPTTP53KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL29803668 | 0.81 | NAMPT (0.49) | MAPTTP53KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL24669288 | 0.81 | NAMPT (0.49) | MAPTTP53KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL24669305 | 0.81 | KDM4E (0.48) | MAPTSMN1; SMN2ALDH1A1L3MBTL1MAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |