Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | WDR5 | P61964 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | F13A1 | P00488 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | TGM1 | P22735 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24670246 | 0.88 | NAMPT (0.47) | L3MBTL1USP30NPY2RWDR5CHRM1 | |
| SCHEMBL24669396 | 0.88 | NAMPT (0.47) | L3MBTL1USP30NPY2RWDR5CHRM1 | |
| SCHEMBL29803242 | 0.86 | MAPKAPK2 (0.47) | L3MBTL1WDR5CHRM1CCNT1CDK9 | |
| SCHEMBL29803687 | 0.86 | MAPKAPK2 (0.47) | L3MBTL1WDR5CHRM1CCNT1CDK9 | |
| SCHEMBL24670910 | 0.86 | MAPKAPK2 (0.47) | L3MBTL1WDR5CHRM1CCNT1CDK9 | |
| SCHEMBL24670180 | 0.86 | HDAC1 (0.42) | CCNT1CDK9MAPK14NPC1NAMPT | |
| SCHEMBL24671575 | 0.84 | MAPT (0.42) | L3MBTL1NPY2RWDR5F13A1TGM2 | |
| SCHEMBL24671474 | 0.83 | WNT3A (0.45) | F13A1TGM2TGM1CCNT1CDK9 | |
| SCHEMBL24670908 | 0.82 | NAMPT (0.46) | L3MBTL1USP30NPY2RWDR5CHRM1 | |
| SCHEMBL29804024 | 0.81 | CCNT1 (0.51) | CCNT1CDK9NPC1LMNANAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |