Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.34 |
| ▸ | CDK7 | P50613 | 1/20 | 0.33 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.33 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 6/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 6/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | WDR5 | P61964 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24671140 | 0.86 | NAMPT (0.39) | NAMPTSOS1CDK7CDK13CDK12 | |
| SCHEMBL29803817 | 0.85 | NAMPT (0.38) | NAMPTCDK9PDK4WDR5 | |
| SCHEMBL24670909 | 0.85 | NAMPT (0.38) | NAMPTCDK9PDK4WDR5 | |
| SCHEMBL24670827 | 0.85 | NAMPT (0.38) | NAMPTCDK9PDK4WDR5 | |
| SCHEMBL24670320 | 0.85 | NAMPT (0.39) | NAMPTSOS1CDK7CDK13CDK12 | |
| SCHEMBL24670022 | 0.84 | NAMPT (0.42) | NAMPTSOS1CDK7CDK13CDK12 | |
| SCHEMBL29803756 | 0.82 | NAMPT (0.39) | NAMPTCDK9PDK4 | |
| SCHEMBL24670284 | 0.81 | SCN9A (0.38) | NAMPTCDK7CDK13CDK12PTGER4 | |
| SCHEMBL24670115 | 0.81 | NAMPT (0.43) | NAMPTSOS1CDK7CDK13CDK12 | |
| SCHEMBL24667840 | 0.79 | CDK9 (0.41) | NAMPTSOS1CDK7CDK13CDK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |