Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 4/20 | 0.44 |
| ▸ | NAMPT | P43490 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24670895 | 0.86 | TMPRSS2 (0.44) | TMPRSS2NAMPTMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL24671339 | 0.85 | MAPT (0.41) | TMPRSS2NAMPTMAPTSMN1; SMN2NPC1 | |
| SCHEMBL24667821 | 0.85 | TMPRSS2 (0.54) | TMPRSS2NAMPTMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL24669387 | 0.84 | TMPRSS2 (0.45) | TMPRSS2NAMPTMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL24891885 | 0.84 | TMPRSS2 (0.45) | TMPRSS2NAMPTMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL24891899 | 0.78 | TMPRSS2 (0.47) | TMPRSS2NAMPTMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL30181068 | 0.78 | TMPRSS2 (0.49) | TMPRSS2NAMPT | |
| SCHEMBL24891895 | 0.78 | TMPRSS2 (0.49) | TMPRSS2NAMPT | |
| SCHEMBL24670896 | 0.78 | TMPRSS2 (0.46) | TMPRSS2NAMPTMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL30181035 | 0.78 | NAMPT (0.43) | TMPRSS2NAMPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |