Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 3/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.35 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.35 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | ESRRG | P62508 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29803264 | 0.86 | RXFP1 (0.34) | MAPTKDM4ELMNASMN1; SMN2TMPRSS2 | |
| SCHEMBL24670918 | 0.85 | TMPRSS2 (0.44) | MAPTKDM4ELMNASMN1; SMN2TMPRSS2 | |
| SCHEMBL24671416 | 0.85 | TP53 (0.37) | KDM4ELMNASMN1; SMN2TMPRSS2NPC1 | |
| SCHEMBL24671549 | 0.84 | TP53 (0.40) | MAPTKDM4ELMNASMN1; SMN2TMPRSS2 | |
| SCHEMBL29803084 | 0.83 | ESRRG (0.46) | MAPTKDM4ELMNASMN1; SMN2MEN1 | |
| Trifluoroacetic Acid SCHEMBL29803711 | 0.81 | TP53 (0.36) | SMN1; SMN2NPC1NAMPTRXFP1HDAC3 | |
| SCHEMBL24669283 | 0.80 | NAMPT (0.45) | MAPTKDM4ELMNASMN1; SMN2NAMPT | |
| SCHEMBL24669980 | 0.78 | RXFP1 (0.34) | MAPTKDM4ELMNASMN1; SMN2MEN1 | |
| SCHEMBL24671418 | 0.75 | TP53 (0.39) | MAPTKDM4ELMNASMN1; SMN2MEN1 | |
| SCHEMBL24669235 | 0.75 | TRPV1 (0.41) | MAPTTMPRSS2ESRRGTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | claimed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |