Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 12/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 2/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24671010 | 0.96 | WNT3A (0.37) | WNT3ANAMPTHDAC1HDAC6MAPT | |
| SCHEMBL24671038 | 0.90 | WNT3A (0.33) | WNT3ANAMPTROCK2KIT | |
| SCHEMBL24669232 | 0.86 | NAMPT (0.39) | WNT3ANAMPTHDAC1HDAC6MAPT | |
| SCHEMBL29803669 | 0.86 | NAMPT (0.39) | WNT3ANAMPTHDAC1HDAC6MAPT | |
| SCHEMBL24671548 | 0.85 | NAMPT (0.39) | WNT3ANAMPTHDAC1HDAC6MAPT | |
| SCHEMBL24669388 | 0.85 | NAMPT (0.44) | WNT3ANAMPTHDAC1HDAC6MAPT | |
| SCHEMBL30182331 | 0.85 | NAMPT (0.44) | WNT3ANAMPTHDAC1HDAC6MAPT | |
| SCHEMBL24669386 | 0.85 | NAMPT (0.44) | WNT3ANAMPTHDAC1HDAC6MAPT | |
| SCHEMBL24670464 | 0.84 | HDAC3 (0.40) | WNT3ANAMPTHDAC1HDAC6MAPT | |
| SCHEMBL24669894 | 0.84 | HDAC3 (0.40) | WNT3ANAMPTHDAC1HDAC6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |