SCHEMBL24671038

CC(C)(C)OC(=O)/N=C(\NCc1ccc(NC(=O)c2nc(C3=CCN(/C(=N/C(=O)OC(C)(C)CCC(C)(C)OC(=O)/N=C(\NC(=O)OC(C)(C)C)n4cccn4)NC(=O)OC(C)(C)C)CC3)cs2)cc1)NC(=O)OC(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 4)

	gene	UniProt	supporting neighbours	confidence
▸	WNT3A	P56704	1/20	0.33

▸	NAMPT	P43490	2/20	0.33

▸	ROCK2	O75116	1/20	0.32

▸	KIT	P10721	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL24671008	0.90	WNT3A (0.37)	WNT3ANAMPTROCK2KIT
SCHEMBL24671010	0.87	WNT3A (0.37)	WNT3ANAMPTROCK2KIT
SCHEMBL24669232	0.79	NAMPT (0.39)	WNT3ANAMPTKIT
SCHEMBL29803669	0.79	NAMPT (0.39)	WNT3ANAMPTKIT
SCHEMBL24671548	0.77	NAMPT (0.39)	WNT3ANAMPTROCK2KIT
SCHEMBL24669388	0.77	NAMPT (0.44)	WNT3ANAMPT
SCHEMBL30182331	0.77	NAMPT (0.44)	WNT3ANAMPT
SCHEMBL24669386	0.77	NAMPT (0.44)	WNT3ANAMPT
SCHEMBL24669894	0.76	HDAC3 (0.40)	WNT3ANAMPTROCK2KIT
SCHEMBL24670464	0.76	HDAC3 (0.40)	WNT3ANAMPTROCK2KIT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2022192162-A1	NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE	FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US)	2022-09-15	—	—	WO	disclosed