Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.46 |
| ▸ | FPR2 | P25090 | 6/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | FPR3 | P25089 | 5/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | LEF1 | Q9UJU2 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24669864 | 0.89 | NAMPT (0.50) | NAMPTFPR2FPR3HDAC1HDAC6 | |
| SCHEMBL24669430 | 0.82 | NAMPT (0.55) | NAMPTFPR2CA1CA2FPR3 | |
| SCHEMBL24669866 | 0.82 | NAMPT (0.51) | NAMPTFPR2CA1CA2PTGER4 | |
| SCHEMBL24670295 | 0.79 | RAB9A (0.53) | NAMPTFPR2CA1CA2FPR3 | |
| SCHEMBL24671047 | 0.79 | RAB9A (0.56) | NAMPTLMNAALDH1A1 | |
| SCHEMBL1065312 | 0.78 | CA2 (0.55) | NAMPTFPR2CA1CA2FPR3 | |
| SCHEMBL2873843 | 0.77 | NAMPT (0.64) | NAMPTHDAC1 | |
| SCHEMBL24669863 | 0.77 | NAMPT (0.53) | NAMPTCA1CA2LMNAALDH1A1 | |
| SCHEMBL29803548 | 0.77 | NAMPT (0.53) | NAMPTCA1CA2LMNAALDH1A1 | |
| SCHEMBL19889037 | 0.77 | NAMPT (0.60) | NAMPTFPR2CA1CA2FPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |