Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6814592 | 0.81 | RAB9A (0.64) | POLBNPC1KMT2AALDH1A1MAPT | |
| SCHEMBL15498718 | 0.77 | S1PR4 (0.51) | POLBKMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL1179297 | 0.77 | KMT2A (0.54) | NPC1KMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL24670292 | 0.76 | SMN1; SMN2 (0.58) | POLBNPC1KMT2AALDH1A1MAPT | |
| SCHEMBL17680509 | 0.74 | POLB (0.53) | POLBNPC1KMT2AALDH1A1MAPT | |
| SCHEMBL24671047 | 0.74 | RAB9A (0.56) | POLBNPC1KMT2AALDH1A1MAPT | |
| SCHEMBL16142979 | 0.74 | ALDH1A1 (0.58) | NPC1KMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL6624469 | 0.73 | GAA (0.40) | POLBNPC1KMT2AALDH1A1MEN1 | |
| SCHEMBL109822 | 0.73 | GAA (0.48) | POLBNPC1KMT2AALDH1A1MAPT | |
| SCHEMBL17215044 | 0.71 | GAA (0.57) | POLBNPC1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |