Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.50 |
| ▸ | WNT3A | P56704 | 1/20 | 0.45 |
| ▸ | KIT | P10721 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CDK7 | P50613 | 1/20 | 0.39 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.39 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.39 |
| ▸ | LIPC | P11150 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24671267 | 0.92 | NAMPT (0.49) | NAMPTWNT3AKITGPR119CDK7 | |
| SCHEMBL24669223 | 0.90 | NAMPT (0.61) | NAMPTWNT3AKITGPR119CDK7 | |
| SCHEMBL24670226 | 0.86 | NAMPT (0.57) | NAMPTWNT3AKITSMN1; SMN2HDAC1 | |
| SCHEMBL24892276 | 0.86 | NAMPT (0.57) | NAMPTWNT3AKITSMN1; SMN2HDAC1 | |
| SCHEMBL24670346 | 0.85 | NAMPT (0.48) | NAMPTWNT3AKITSMN1; SMN2MEN1 | |
| SCHEMBL30182548 | 0.85 | NAMPT (0.54) | NAMPTWNT3AKITSMN1; SMN2HDAC1 | |
| SCHEMBL24669232 | 0.84 | NAMPT (0.39) | NAMPTWNT3AKITHDAC1HDAC6 | |
| SCHEMBL29803669 | 0.84 | NAMPT (0.39) | NAMPTWNT3AKITHDAC1HDAC6 | |
| SCHEMBL29803758 | 0.83 | NAMPT (0.48) | NAMPTWNT3AKITSMN1; SMN2HDAC1 | |
| SCHEMBL24670971 | 0.83 | WNT3A (0.47) | NAMPTWNT3AKITGPR119MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |