Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 3/20 | 0.45 |
| ▸ | KIT | P10721 | 2/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.42 |
| ▸ | GRM1 | Q13255 | 8/20 | 0.42 |
| ▸ | GRM5 | P41594 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24670988 | 0.86 | NAMPT (0.40) | WNT3ANAMPTMAPTTDP1 | |
| SCHEMBL24671008 | 0.84 | WNT3A (0.37) | WNT3ANAMPTKITMAPTTDP1 | |
| SCHEMBL24670346 | 0.83 | NAMPT (0.48) | WNT3ANAMPTKITGRM1GRM5 | |
| SCHEMBL24671070 | 0.83 | NAMPT (0.50) | WNT3ANAMPTKITGPR119GRM1 | |
| SCHEMBL24671010 | 0.82 | WNT3A (0.37) | WNT3ANAMPTKITGPR119MAPT | |
| SCHEMBL24670226 | 0.82 | NAMPT (0.57) | WNT3ANAMPTKITGPR119MAPT | |
| SCHEMBL24892276 | 0.82 | NAMPT (0.57) | WNT3ANAMPTKITGPR119MAPT | |
| SCHEMBL29803758 | 0.81 | NAMPT (0.48) | WNT3ANAMPTKITGPR119GRM1 | |
| SCHEMBL24891816 | 0.81 | NAMPT (0.47) | WNT3ANAMPTKITGRM1GRM5 | |
| SCHEMBL24670337 | 0.80 | NAMPT (0.49) | WNT3ANAMPTKITGRM1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |