Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | LPL | P06858 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5085882 | 0.84 | TRPA1 (0.40) | USP2ALDH1A1L3MBTL1LMNAMAPT | |
| SCHEMBL7672096 | 0.75 | MAPT (0.45) | TSHRALDH1A1L3MBTL1LMNAMAPT | |
| SCHEMBL8459678 | 0.74 | TRPA1 (0.41) | ALDH1A1L3MBTL1LMNAMAPTHPGD | |
| SCHEMBL28425604 | 0.73 | CDK1 (0.40) | ALDH1A1LMNALPLLIPGACHE | |
| SCHEMBL9569026 | 0.73 | CNR1 (0.37) | ALDH1A1LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL10497451 | 0.72 | SRC (0.42) | ALDH1A1L3MBTL1LMNAMAPTHPGD | |
| SCHEMBL2704056 | 0.71 | ALDH1A1 (0.45) | USP2TSHRALDH1A1L3MBTL1LMNA | |
| SCHEMBL5250728 | 0.70 | TRPA1 (0.41) | USP2ALDH1A1L3MBTL1LMNAMAPT | |
| SCHEMBL8722809 | 0.70 | ALDH1A1 (0.40) | TSHRNPSR1ALDH1A1L3MBTL1LMNA | |
| SCHEMBL12910454 | 0.69 | CHRNB2 (0.50) | TSHRALDH1A1CHRNB2CHRNA4LPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022235715-A1 | COMPOUNDS FOR INHIBITING OR DEGRADING ITK, COMPOSITIONS, COMPRISING THE SAME METHODS OF THEIR MAKING AND METHODS OF THEIR USE | NURIX THERAPEUTICS, INC. (US) | 2022-11-10 | — | — | WO | disclosed |