Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 8/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 7/20 | 0.36 |
| ▸ | NAMPT | P43490 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24670237 | 1.00 | CDK9 (0.36) | CDK9CCNT1NAMPTNPC1TRPV1 | |
| SCHEMBL24670242 | 0.93 | NPC1 (0.35) | CDK9CCNT1NAMPTNPC1TRPV1 | |
| SCHEMBL24671182 | 0.93 | NAMPT (0.38) | CDK9CCNT1NAMPTNPC1TRPV1 | |
| SCHEMBL29803596 | 0.93 | NAMPT (0.38) | CDK9CCNT1NAMPTNPC1TRPV1 | |
| SCHEMBL24669435 | 0.89 | NAMPT (0.42) | NAMPT | |
| SCHEMBL24669444 | 0.89 | NAMPT (0.42) | NAMPT | |
| SCHEMBL24671294 | 0.89 | MAPT (0.37) | NAMPTNPC1ALDH1A1MAPT | |
| SCHEMBL24671551 | 0.89 | WDR5 (0.36) | CDK9CCNT1NAMPTNPC1TRPV1 | |
| SCHEMBL24670926 | 0.89 | WDR5 (0.36) | CDK9CCNT1NAMPTNPC1TRPV1 | |
| SCHEMBL24670858 | 0.89 | NAMPT (0.37) | CDK9CCNT1NAMPTPDK4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |