Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP3 | P08254 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 6/20 | 0.35 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.35 |
| ▸ | HTR1D | P28221 | 3/20 | 0.35 |
| ▸ | HTR1B | P28222 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24671362 | 0.94 | MMP2 (0.40) | MMP2MMP3F2F10PLG | |
| SCHEMBL24671333 | 0.84 | MAPT (0.41) | MMP2MMP3F2F10PLG | |
| SCHEMBL24671353 | 0.84 | TMPRSS2 (0.43) | MMP2MMP3F2F10PLG | |
| SCHEMBL24670308 | 0.81 | TRPV1 (0.45) | MMP2MMP3NAMPTMAPTLMNA | |
| SCHEMBL29803440 | 0.80 | NAMPT (0.50) | NAMPT | |
| SCHEMBL24669458 | 0.78 | TMPRSS2 (0.48) | F2PLGPLAUPLATNAMPT | |
| SCHEMBL24670299 | 0.77 | MAPT (0.46) | MMP2MMP3NAMPTTMPRSS2MAPT | |
| SCHEMBL24671261 | 0.77 | QDPR (0.43) | PLAUPLATNAMPTTMPRSS2HTR1D | |
| SCHEMBL24669447 | 0.76 | TMPRSS2 (0.48) | NAMPTTMPRSS2MAPTLMNAHTT | |
| SCHEMBL29803214 | 0.76 | TMPRSS2 (0.52) | PLAUNAMPTTMPRSS2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |