Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 1/20 | 0.43 |
| ▸ | TMPRSS2 | O15393 | 4/20 | 0.42 |
| ▸ | NAMPT | P43490 | 3/20 | 0.42 |
| ▸ | KLK1 | P06870 | 1/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.39 |
| ▸ | CDK9 | P50750 | 2/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24670801 | 0.90 | TMPRSS2 (0.45) | QDPRTMPRSS2NAMPTHTR1DSLC6A4 | |
| SCHEMBL29802916 | 0.90 | TMPRSS2 (0.43) | TMPRSS2NAMPTKLK1KLK5CCNT1 | |
| SCHEMBL24671333 | 0.89 | MAPT (0.41) | TMPRSS2NAMPTKLK1KLK5CCNT1 | |
| SCHEMBL29802957 | 0.89 | TMPRSS2 (0.44) | TMPRSS2NAMPTKLK1KLK5CCNT1 | |
| SCHEMBL24669441 | 0.88 | TMPRSS2 (0.53) | QDPRTMPRSS2NAMPTHTR1DSLC6A4 | |
| SCHEMBL24670299 | 0.87 | MAPT (0.46) | TMPRSS2NAMPTCCNT1CDK9MAPT | |
| SCHEMBL24669408 | 0.86 | NAMPT (0.50) | QDPRNAMPTCDK9MAPT | |
| SCHEMBL24671177 | 0.86 | TMPRSS2 (0.51) | TMPRSS2NAMPTHTR1DSLC6A4PLAU | |
| SCHEMBL29803211 | 0.86 | TMPRSS2 (0.51) | TMPRSS2NAMPTHTR1DSLC6A4PLAU | |
| SCHEMBL24671552 | 0.85 | CCNT1 (0.42) | TMPRSS2KLK1KLK5CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | claimed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |