Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PTGFR | P43088 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29803694 | 1.00 | LMNA (0.52) | LMNASMN1; SMN2HTTMAOBNPC1 | |
| SCHEMBL29803767 | 0.86 | RAB9A (0.56) | LMNASMN1; SMN2HTTNPC1RAB9A | |
| SCHEMBL24669477 | 0.81 | RAB9A (0.53) | LMNASMN1; SMN2MAOBNPC1RAB9A | |
| SCHEMBL24670735 | 0.77 | MAOB (0.62) | LMNASMN1; SMN2HTTMAOBNPC1 | |
| SCHEMBL24670924 | 0.75 | RAB9A (0.69) | LMNASMN1; SMN2HTTMAOBNPC1 | |
| SCHEMBL1137180 | 0.75 | MAOB (0.51) | LMNASMN1; SMN2HTTMAOBNPC1 | |
| SCHEMBL15527824 | 0.74 | RAB9A (0.63) | LMNASMN1; SMN2HTTNPC1RAB9A | |
| SCHEMBL24670851 | 0.74 | MAOB (0.59) | LMNASMN1; SMN2HTTMAOBNPC1 | |
| SCHEMBL29803287 | 0.74 | MAOB (0.59) | LMNASMN1; SMN2HTTMAOBNPC1 | |
| SCHEMBL24669338 | 0.74 | MAOB (0.70) | LMNASMN1; SMN2HTTMAOBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |