Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | GPR27 | Q9NS67 | 3/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | PTGFR | P43088 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24670924 | 0.87 | RAB9A (0.69) | RAB9AKMT2ANPC1LMNAALDH1A1 | |
| SCHEMBL29803598 | 0.87 | RAB9A (0.62) | RAB9AKMT2ANPC1LMNAALDH1A1 | |
| SCHEMBL24670991 | 0.84 | RAB9A (0.56) | RAB9AKMT2ANPC1LMNAALDH1A1 | |
| SCHEMBL24670251 | 0.81 | POLB (0.56) | RAB9AKMT2ANPC1LMNAALDH1A1 | |
| SCHEMBL29803460 | 0.81 | KMT2A (0.51) | RAB9AKMT2ANPC1LMNAALDH1A1 | |
| SCHEMBL24669366 | 0.81 | KMT2A (0.51) | RAB9AKMT2ANPC1LMNAALDH1A1 | |
| SCHEMBL29803694 | 0.81 | LMNA (0.52) | RAB9AKMT2ANPC1LMNAALDH1A1 | |
| SCHEMBL24671377 | 0.81 | LMNA (0.52) | RAB9AKMT2ANPC1LMNAALDH1A1 | |
| SCHEMBL24670735 | 0.80 | MAOB (0.62) | RAB9AKMT2ANPC1LMNASMN1; SMN2 | |
| SCHEMBL19350786 | 0.78 | GPR27 (0.74) | RAB9AKMT2ANPC1ALDH1A1GPR27 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |