Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TMPRSS2 | O15393 | 4/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24671336 | 0.86 | TMPRSS2 (0.52) | TP53MAPTSMN1; SMN2TMPRSS2CYP2C9 | |
| SCHEMBL24670304 | 0.84 | NAMPT (0.51) | TP53MAPTTHRBSMN1; SMN2CYP2C9 | |
| SCHEMBL24671463 | 0.84 | TMPRSS2 (0.49) | TP53MAPTTHRBSMN1; SMN2TMPRSS2 | |
| SCHEMBL24671380 | 0.82 | MAPT (0.53) | TP53MAPTSMN1; SMN2TMPRSS2CYP2C9 | |
| SCHEMBL24667821 | 0.81 | TMPRSS2 (0.54) | MAPTSMN1; SMN2TMPRSS2 | |
| SCHEMBL24669609 | 0.79 | TMPRSS2 (0.45) | MAPTTMPRSS2NPY2R | |
| SCHEMBL24671018 | 0.79 | SMN1; SMN2 (0.43) | MAPTSMN1; SMN2TMPRSS2NPY2R | |
| SCHEMBL24670255 | 0.79 | TMPRSS2 (0.45) | MAPTTMPRSS2NPY2R | |
| SCHEMBL29802911 | 0.78 | TMPRSS2 (0.41) | MAPTSMN1; SMN2TMPRSS2NPY2RTAAR1 | |
| SCHEMBL24671240 | 0.78 | TMPRSS2 (0.46) | TMPRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | claimed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |