Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 5/20 | 0.49 |
| ▸ | HTR1D | P28221 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | QDPR | P09417 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24671336 | 0.88 | TMPRSS2 (0.52) | TMPRSS2HTR1DSLC6A4CHRM1NPY2R | |
| SCHEMBL24669441 | 0.88 | TMPRSS2 (0.53) | TMPRSS2HTR1DSLC6A4SMN1; SMN2ALDH1A1 | |
| SCHEMBL24671330 | 0.85 | TMPRSS2 (0.46) | TMPRSS2HTR1DSLC6A4CHRM1SMN1; SMN2 | |
| SCHEMBL24670887 | 0.85 | NAMPT (0.52) | TMPRSS2HTR1DSLC6A4CHRM1NPY2R | |
| SCHEMBL24671567 | 0.84 | TP53 (0.47) | TMPRSS2NPY2RSMN1; SMN2MAPTTP53 | |
| SCHEMBL29802891 | 0.84 | APOBEC3A (0.49) | TMPRSS2HTR1DSLC6A4CHRM1NPY2R | |
| SCHEMBL24671380 | 0.82 | MAPT (0.53) | TMPRSS2SMN1; SMN2ALDH1A1MAPTHPGD | |
| SCHEMBL24667821 | 0.81 | TMPRSS2 (0.54) | TMPRSS2SMN1; SMN2ALDH1A1MAPTHPGD | |
| SCHEMBL24670801 | 0.80 | TMPRSS2 (0.45) | TMPRSS2HTR1DSLC6A4CHRM1SMN1; SMN2 | |
| SCHEMBL24670178 | 0.79 | TMPRSS2 (0.52) | TMPRSS2HTR1DSLC6A4MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | claimed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |