Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 3/20 | 0.47 |
| ▸ | GRM5 | P41594 | 4/20 | 0.44 |
| ▸ | GRM1 | Q13255 | 4/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | F13A1 | P00488 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | TGM1 | P22735 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29803476 | 0.89 | NAMPT (0.49) | WNT3AGRM5GRM1JAK1SCN9A | |
| SCHEMBL24671474 | 0.88 | WNT3A (0.45) | WNT3ASMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL24671394 | 0.85 | WNT3A (0.36) | WNT3AJAK1SCN9ACDK9 | |
| SCHEMBL24670950 | 0.85 | WNT3A (0.36) | WNT3AJAK1SCN9ACDK9 | |
| SCHEMBL29803582 | 0.85 | GRM1 (0.47) | WNT3AGRM5GRM1JAK1SCN9A | |
| SCHEMBL24671417 | 0.85 | GRM1 (0.47) | WNT3AGRM5GRM1JAK1SCN9A | |
| SCHEMBL24671581 | 0.85 | JAK1 (0.45) | GRM5GRM1JAK1SCN9ACDK9 | |
| SCHEMBL24671480 | 0.84 | GRM1 (0.49) | WNT3AGRM5GRM1JAK1SCN9A | |
| SCHEMBL29803325 | 0.84 | GRM1 (0.49) | WNT3AGRM5GRM1JAK1SCN9A | |
| SCHEMBL24671395 | 0.84 | WNT3A (0.41) | WNT3ACDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |