Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 7/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | F13A1 | P00488 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | TGM1 | P22735 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24671578 | 0.88 | WNT3A (0.47) | WNT3ASMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL24670947 | 0.86 | CCNT1 (0.45) | CCNT1CDK9FLT3 | |
| SCHEMBL29803783 | 0.86 | CCNT1 (0.45) | CCNT1CDK9FLT3 | |
| SCHEMBL24671017 | 0.83 | L3MBTL1 (0.42) | SMN1; SMN2MEN1KMT2AMAPTTSHR | |
| SCHEMBL24671033 | 0.82 | GRM1 (0.44) | CCNT1CDK9NAMPT | |
| SCHEMBL24671483 | 0.81 | JAK1 (0.42) | CCNT1CDK9NAMPT | |
| SCHEMBL24671032 | 0.81 | WNT3A (0.52) | WNT3ASMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL29803282 | 0.77 | CCNT1 (0.49) | WNT3ASMN1; SMN2TSHRCCNT1CDK9 | |
| SCHEMBL24670180 | 0.77 | HDAC1 (0.42) | CCNT1CDK9NAMPT | |
| SCHEMBL29803476 | 0.77 | NAMPT (0.49) | WNT3ACCNT1CDK9NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |