Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | APP | P05067 | 5/20 | 0.50 |
| ▸ | CNR1 | P21554 | 2/20 | 0.49 |
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | PDE2A | O00408 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | AGXT | P21549 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29360199 | 1.00 | NPC1 (0.56) | NPC1RAB9AALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL10055039 | 0.87 | NPC1 (0.68) | NPC1RAB9AALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL223680 | 0.81 | ALDH1A1 (0.61) | NPC1RAB9AALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL29816629 | 0.81 | ALDH1A1 (0.61) | NPC1RAB9AALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL31080534 | 0.80 | NPC1 (0.61) | NPC1RAB9AAPPCNR1CNR2 | |
| SCHEMBL2176479 | 0.80 | MAOB (0.58) | NPC1RAB9AAPPMAOBABCB1 | |
| SCHEMBL13513303 | 0.79 | NPC1 (0.55) | NPC1ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL21132339 | 0.79 | SYK (0.49) | NPC1ALDH1A1CYP2D6CYP2C19LMNA | |
| SCHEMBL510090 | 0.79 | NPC1 (0.63) | NPC1RAB9AALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL510400 | 0.79 | NPC1 (0.58) | NPC1RAB9AALDH1A1CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4746871-A2 | METHOD OF ENHANCED ABSORPTION OF QUINOXALINE TYPE III RECEPTOR TYROSINE KINASE INHIBITORS | ELIXIRON IMMUNOTHERAPEUTICS INC. (TW) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025019622-A2 | METHOD OF ENHANCED ABSORPTION OF QUINOXALINE TYPE III RECEPTOR TYROSINE KINASE INHIBITORS | ELIXIRON IMMUNOTHERAPEUTICS INC. (TW) | 2025-01-23 | — | — | WO | disclosed |
| CN-115803316-A | Pyridone compound and preparation method and application thereof | 深圳晶泰科技有限公司 | 2023-03-14 | — | — | CN | disclosed |
| CN-105777464-B | Hydroxamic acid derivative and preparation method and application thereof | 中国科学院上海药物研究所 | 2020-09-29 | — | — | CN | disclosed |
| EP-2542077-A1 | INHIBITORS OF CATECHOL O-METHYL TRANSFERASE AND THEIR USE IN THE TREATMENT OF PSYCHOTIC DISORDERS | Merck Sharp & Dohme Corp. (US) | 2013-01-09 | — | — | EP | disclosed |
| WO-2011109261-A1 | INHIBITORS OF CATECHOL O-METHYL TRANSFERASE AND THEIR USE IN THE TREATMENT OF PSYCHOTIC DISORDERS | MERCK SHARP & DOHME CORP. (US) | 2011-09-09 | — | — | WO | disclosed |
| CN-101626686-A | 3-substituent-1, 2, 3-benzotriazinone compounds for improving glutaminic synaptic responses | CORTEX PHARMA INC | 2010-01-13 | — | — | CN | disclosed |
| US-4728668-A | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments | USV PHARMACEUTICAL CORPORATION (US) | 1988-03-01 | — | — | US | disclosed |
| US-4725619-A | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments | USV PHARMACEUTICAL CORPORATION (US) | 1988-02-16 | — | — | US | disclosed |
| US-4631287-A | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments | USV PHARMACEUTICAL CORP. (US) | 1986-12-23 | — | — | US | disclosed |
| EP-0200101-A2 | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive aliments | USV PHARMACEUTICAL CORPORATION (US) | 1986-11-05 | — | — | EP | disclosed |