Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.32 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25502168 | 0.95 | GNAI3 (0.37) | NPC1MEN1KMT2AGNAI3GNAO1 | |
| SCHEMBL23484948 | 0.88 | NPC1 (0.36) | NPC1MEN1KMT2AGNAI3GNAO1 | |
| SCHEMBL23594109 | 0.87 | ALDH1A1 (0.36) | NPC1MEN1KMT2AGNAI3GNAO1 | |
| SCHEMBL25851958 | 0.85 | ALDH1A1 (0.36) | NPC1MEN1KMT2AGNAI3GNAO1 | |
| SCHEMBL8283986 | 0.84 | NPC1 (0.42) | NPC1KMT2AGNAI3GNAO1GNAI1 | |
| SCHEMBL26804302 | 0.84 | ALDH1A1 (0.40) | NPC1MEN1KMT2AGNAI3GNAO1 | |
| SCHEMBL25030012 | 0.83 | NPC1 (0.39) | NPC1GNAI3GNAO1GNAI1ALDH1A1 | |
| SCHEMBL26221592 | 0.83 | NPC1 (0.39) | NPC1MEN1KMT2AGNAI3GNAO1 | |
| SCHEMBL26707720 | 0.83 | CACNA1G (0.41) | MEN1KMT2AALDH1A1CACNA1G | |
| SCHEMBL23484939 | 0.82 | GNAI3 (0.38) | NPC1MEN1KMT2AGNAI3GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022235715-A1 | COMPOUNDS FOR INHIBITING OR DEGRADING ITK, COMPOSITIONS, COMPRISING THE SAME METHODS OF THEIR MAKING AND METHODS OF THEIR USE | NURIX THERAPEUTICS, INC. (US) | 2022-11-10 | — | — | WO | disclosed |