Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.32 |
| ▸ | PGK1 | P00558 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | METAP2 | P50579 | 1/20 | 0.30 |
| ▸ | METAP1 | P53582 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23326569 | 0.78 | LRRK2 (0.32) | YTHDC1PGK1PDK2METAP2METAP1 | |
| SCHEMBL10252220 | 0.78 | TDP1 (0.35) | PDK2 | |
| SCHEMBL12303154 | 0.77 | PDK2 (0.36) | YTHDC1PGK1PDK2METAP2METAP1 | |
| SCHEMBL7298442 | 0.74 | KMT2A (0.34) | YTHDC1PGK1PDK2METAP2METAP1 | |
| SCHEMBL3120330 | 0.72 | PDE10A (0.49) | — | |
| SCHEMBL4289488 | 0.72 | TDP1 (0.31) | — | |
| SCHEMBL30853310 | 0.71 | LMNA (0.31) | YTHDC1PGK1PDK2 | |
| SCHEMBL24671926 | 0.71 | LRRK2 (0.31) | YTHDC1PGK1PDK2 | |
| SCHEMBL25207734 | 0.69 | PDK2 (0.30) | PDK2 | |
| SCHEMBL23326581 | 0.69 | CA1 (0.34) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022170802-A1 | PYRIMIDO-PYRIDONE DERIVATIVE AS SOS1 INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州阿尔脉生物科技有限公司 | 2022-08-18 | — | — | WO | disclosed |