Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.30 |
| ▸ | PGK1 | P00558 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27186160 | 1.00 | LMNA (0.31) | LMNAHTTSMN1; SMN2PDK2PDK4 | |
| SCHEMBL27186297 | 0.82 | PDK2 (0.32) | LMNAHTTSMN1; SMN2PDK2PDK4 | |
| SCHEMBL29844244 | 0.82 | PDK2 (0.32) | LMNAHTTSMN1; SMN2PDK2PDK4 | |
| SCHEMBL2179135 | 0.79 | PDK2 (0.32) | PDK2PGK1 | |
| SCHEMBL12303154 | 0.74 | PDK2 (0.36) | PDK2PDK4YTHDC1PGK1 | |
| SCHEMBL22119996 | 0.72 | LMNA (0.39) | LMNA | |
| SCHEMBL23326569 | 0.71 | LRRK2 (0.32) | PDK2YTHDC1PGK1 | |
| SCHEMBL7298442 | 0.71 | KMT2A (0.34) | HTTPDK2YTHDC1PGK1 | |
| SCHEMBL24671925 | 0.71 | YTHDC1 (0.32) | PDK2YTHDC1PGK1 | |
| SCHEMBL29844264 | 0.69 | PIK3CA (0.34) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117651701-A | Novel substituted bicyclic aza heterocycles as SOS1 inhibitors | 唯久生物技术(苏州)有限公司 | 2024-03-05 | — | — | CN | disclosed |