Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.30 |
| ▸ | PGK1 | P00558 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25207734 | 0.82 | PDK2 (0.30) | PDK2PDK4 | |
| SCHEMBL23326581 | 0.82 | CA1 (0.34) | PDK2PDK4 | |
| SCHEMBL22843514 | 0.82 | YTHDC1 (0.38) | YTHDC1PGK1 | |
| SCHEMBL24672012 | 0.75 | HTT (0.33) | — | |
| SCHEMBL23326490 | 0.74 | L3MBTL1 (0.42) | PDK2 | |
| SCHEMBL19422749 | 0.74 | — | — | |
| SCHEMBL12303154 | 0.74 | PDK2 (0.36) | LRRK2PDK2PDK4YTHDC1PGK1 | |
| SCHEMBL29918598 | 0.72 | CA12 (0.38) | — | |
| SCHEMBL29059996 | 0.72 | KMT2A (0.37) | PDK2 | |
| SCHEMBL30556387 | 0.72 | KMT2A (0.37) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022170802-A1 | PYRIMIDO-PYRIDONE DERIVATIVE AS SOS1 INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州阿尔脉生物科技有限公司 | 2022-08-18 | — | — | WO | disclosed |