Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Resorcinol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CA5A | P35218 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Resorcinol SCHEMBL813556 | 0.95 | ALDH1A1 (0.60) | ALDH1A1CYP3A4CA12CA2CA9 | |
| Resorcinol SCHEMBL8467048 | 0.95 | ALDH1A1 (0.60) | ALDH1A1CYP3A4CA12CA2CA9 | |
| Resorcinol SCHEMBL11784386 | 0.93 | ALDH1A1 (0.52) | ALDH1A1CYP3A4CA12CA2CA9 | |
| Resorcinol SCHEMBL4331126 | 0.88 | ALDH1A1 (0.71) | ALDH1A1CYP3A4CA12CA2CA9 | |
| Resorcinol SCHEMBL31540896 | 0.88 | ALDH1A1 (0.71) | ALDH1A1CYP3A4CA12CA2CA9 | |
| Resorcinol SCHEMBL14332270 | 0.87 | CA12 (0.50) | ALDH1A1CYP3A4CA12CA2CA9 | |
| Ether SCHEMBL6668723 | 0.84 | HSD17B1 (0.60) | ALDH1A1CYP3A4CA12CA2CA9 | |
| Hydroquinone SCHEMBL22289563 | 0.83 | ALDH1A1 (0.63) | ALDH1A1CYP3A4CA12CA2CA9 | |
| Metacresol SCHEMBL8917444 | 0.83 | ACHE (0.71) | ALDH1A1CYP3A4CA12CA2CA9 | |
| Resorcinol SCHEMBL443227 | 0.81 | ALDH1A1 (0.60) | ALDH1A1CYP3A4CA12CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1918317-B1 | Composite material containing non-functional aromatic end group-containing polymer | ROHM & HAAS (US) | 2011-09-14 | — | — | EP | disclosed |
| US-7612145-B2 | Composite material containing non-functional aromatic end group-containing polymer | ROHM AND HAAS COMPANY (US) | 2009-11-03 | — | — | US | disclosed |
| EP-1918317-A2 | Composite material containing non-functional aromatic end group-containing polymer | Rohm and Haas Company (US) | 2008-05-07 | — | — | EP | disclosed |
| US-20080078976-A1 | Composite material containing non-functional aromatic end group-containing polymer | ROHM AND HAAS COMPANY | 2008-04-03 | — | — | US | disclosed |
| US-5854330-A | Capstan comprising polyacetal-based polymer composition for magnetic tape cartridge | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-12-29 | — | — | US | disclosed |
| EP-0733667-A1 | Method for preparing an impact-resistant antistatic polyacetal composition | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-09-25 | — | — | EP | disclosed |
| US-5539054-A | THERMOPLASTIC RESIN AND N-VINYL LACTAM COPOLYMERS WITH TENSILE AND IMPACT STRENGTH | ROHM AND HAAS COMPANY (US) | 1996-07-23 | — | — | US | disclosed |
| US-5446086-A | Molding materials; heat resistance | POLYPLASTICS CO., LTD. (JP) | 1995-08-29 | — | — | US | disclosed |
| EP-0611077-A2 | Polyurethane elastomer blends | ROHM AND HAAS COMPANY (US) | 1994-08-17 | — | — | EP | disclosed |
| EP-0605736-A1 | POLYOXYMETHYLENE COMPOSITION | POLYPLASTICS CO. LTD. (JP) | 1994-07-13 | — | — | EP | disclosed |
| US-5183860-A | Blend with thermoplastic polyurethane | POLYPLASTICS CO., LTD. (JP) | 1993-02-02 | — | — | US | disclosed |
| EP-0449605-A2 | Polyacetal resin composition | POLYPLASTICS CO. LTD. (JP) | 1991-10-02 | — | — | EP | disclosed |
| US-4929712-A | MELT KNEADING THERMOPLASTIC POLYURETHANE, BLENDS, POLYISOCYANATE, POLYISOTHICCYANATE COMPOUNDS | POLYPLASTICS CO., LTD. (JP) | 1990-05-29 | — | — | US | disclosed |
| EP-0350223-A2 | Polyacetal resin composition | POLYPLASTICS CO. LTD. (JP) | 1990-01-10 | — | — | EP | disclosed |