SCHEMBL24672659

SCHEMBL24672659

C[C@H](O)CN1CCN(Cc2cccc(CP(=O)(O)O)c2)CCN(C[C@H](C)O)CC1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PGK1 P00558 3/20 0.47
PGK2 P07205 3/20 0.47
KDM4E B2RXH2 3/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
ALOX15 P16050 1/20 0.43
TSHR P16473 1/20 0.43
CYP2C19 P33261 1/20 0.43
ALDH1A1 P00352 3/20 0.41
TDP1 Q9NUW8 1/20 0.41
DRD2 P14416 2/20 0.41
DRD3 P35462 2/20 0.41
ACP3 P15309 1/20 0.40
HDAC1 Q13547 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
PTPN2 P17706 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24673213 0.86 PGK1 (0.45) PGK1PGK2KDM4EALDH1A1DRD2
SCHEMBL24672961 0.81 ALDH1A1 (0.43) PGK1PGK2KDM4EALOX15TSHR
SCHEMBL1394539 0.77 KDM4E (0.68) KDM4EALDH1A1
SCHEMBL1394677 0.77 KDM4E (0.68) KDM4EALDH1A1
SCHEMBL1394535 0.77 KDM4E (0.68) KDM4EALDH1A1
SCHEMBL21797152 0.77 KDM4E (0.68) KDM4EALDH1A1
SCHEMBL24672242 0.77 KDM4E (0.68) KDM4EALDH1A1
SCHEMBL22014096 0.75 SIGMAR1 (0.49) KDM4ECYP2D6CYP2C9TSHRALDH1A1
SCHEMBL24672959 0.75 HDAC6 (0.43) KDM4EALDH1A1DRD2DRD3HDAC1
SCHEMBL8040890 0.72 PGK1 (0.66) PGK1PGK2ACP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022204065-A1 IRON(III) MACROCYCLIC COMPLEXES WITH MIXED HYROXYL PENDANTS AS MRI CONTRAST AGENTS THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2022-09-29 WO disclosed