Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19822682 | 0.64 | KMT2A (0.36) | ADORA3ADORA1ADORA2AKMT2A | |
| SCHEMBL23599060 | 0.61 | CA1 (0.54) | — | |
| SCHEMBL19659465 | 0.57 | KMT2A (0.64) | ADORA3ADORA1ADORA2AADORA2BMEN1 | |
| SCHEMBL8334814 | 0.56 | PDE9A (0.43) | ADORA1ADORA2AADORA2BMEN1CYP1A2 | |
| SCHEMBL20776751 | 0.56 | YTHDC1 (0.34) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL30956669 | 0.56 | KMT2A (0.38) | ADORA3ADORA1ADORA2AADORA2BKMT2A | |
| SCHEMBL22412912 | 0.56 | KMT2A (0.38) | ADORA3ADORA1ADORA2AADORA2BKMT2A | |
| SCHEMBL22411428 | 0.55 | KMT2A (0.40) | ADORA3ADORA1ADORA2AADORA2BMEN1 | |
| SCHEMBL30873856 | 0.55 | KMT2A (0.40) | ADORA3ADORA1ADORA2AADORA2BMEN1 | |
| SCHEMBL14196007 | 0.54 | IRAK4 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022237747-A1 | SMALL MOLECULAR CD73 ANTAGONIST AND USE THEREOF | 四川海思科制药有限公司 | 2022-11-17 | — | — | WO | disclosed |