Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 3/20 | 0.58 |
| ▸ | CA2 | P00918 | 3/20 | 0.58 |
| ▸ | CA7 | P43166 | 3/20 | 0.58 |
| ▸ | CA9 | Q16790 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3844592 | 0.87 | HTT (0.79) | KMT2AMEN1NPSR1HTTUSP2 | |
| SCHEMBL3838578 | 0.85 | KMT2A (0.70) | KMT2AMEN1NPSR1HTTUSP2 | |
| SCHEMBL12359542 | 0.83 | HTT (0.70) | KMT2AMEN1NPSR1HTTUSP2 | |
| SCHEMBL4818022 | 0.81 | CA1 (0.76) | KMT2AMEN1NPSR1HTTUSP2 | |
| SCHEMBL16783933 | 0.80 | L3MBTL1 (0.64) | KMT2AMEN1NPSR1HTTUSP2 | |
| SCHEMBL16784005 | 0.80 | L3MBTL1 (0.64) | KMT2AMEN1NPSR1HTTUSP2 | |
| SCHEMBL16783932 | 0.80 | L3MBTL1 (0.64) | KMT2AMEN1NPSR1HTTUSP2 | |
| SCHEMBL6192050 | 0.80 | KMT2A (0.78) | KMT2AMEN1NPSR1HTTUSP2 | |
| SCHEMBL3838542 | 0.80 | KMT2A (0.66) | KMT2AMEN1NPSR1HTTUSP2 | |
| SCHEMBL4491381 | 0.79 | LMNA (0.70) | KMT2AMEN1NPSR1HTTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022204065-A1 | IRON(III) MACROCYCLIC COMPLEXES WITH MIXED HYROXYL PENDANTS AS MRI CONTRAST AGENTS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2022-09-29 | — | — | WO | disclosed |